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Last Published: 07-28-12
AMBIT implementation of OpenTox REST API
Two instances of AMBIT REST web services are maintained at IdeaConsult Ltd:
AMBIT REST Web services implement following OpenTox API
Example queries are provided for each resource.
- Compound
- Find a compound by an identifier, e.g.:
- Similarity search in the entire database for SMILES c1ccccc1Oc2ccccc2 and Tanimoto distance >= 0.9
- Substructure search in the entire database for SMARTS [c;R1]1[c;R1][c;R1][c;R1][c;R1][c;R1]1!@[O;H1]
- Feature
- Retrieve all features, representing an EINECS number ( owl:sameAs http://www.opentox.org/api/1.1#EINECS. )
- Retrieve all features of particular dataset (e.g. EPAFHM)
- Retrieve all features, representing readout from a carcinogenicity assay ( owl:sameAs http://www.opentox.org/echaEndpoints.owl#Carcinogenicity. )
- Dataset
- Datasets by endpoints
- First 25 datasets
- List all datasets, with name starting with "EPA"
- First 10 entries from EPAFHM dataset
- Metadata of a particular dataset; the same metadata in N3 format
- Search EPAFHM for compounds with 'inconclusive' activity outcome
- Summary for the values of a given dataset (e.g. EPAFHM) and a feature (e.g. Activity outcome)
- Search for phtalates in ISSCAN dataset.
- Search for phtalates in ISSCAN dataset, and show only CAS, Chemical name and Carcinogenic aactivity.
- Retrieve compounds, grouped by mode of action, as defined in EPAFHM dataset
- Retrieve compounds, grouped by mode of action, as predicted by Toxtree Verhaar scheme model and stored under http://apps.ideaconsult.net:8080/ambit2/feature/823450
- Retrieve compounds from EPAFHM dataset, and display stored and predicted Mode of actions only
- List ToxCast Phase I datasets
- Display estrogen binding activity from KIERBL: EPA Estrogen Receptor Ki Binding Study dataset, for the ToxCast Phase I compounds
- Algorithm
- Model
- Task